РУАЭСТ (RUAEST)
EFFECTS OF EXTERNAL γ-RADIATION ON ADENYLATE CYCLASE ACTIVITY IN SHEEP BLOOD CELLS
In the mechanisms of action of various adverse factors on mammals a special part is assigned to the regulatory systems. The main regulatory system of cellular metabolism is the cAMP system. Exposure of animals to external γ-radiation results in the modification of different biochemical processes in cells. In studying diversified intercellular disorders after irradiation it is, therefore, necessary to assess functioning of the cAMP system and its key enzyme, the adenylate cyclase. Note that the data published on the effect of γ-irradiation are mainly obtained with laboratory animals which are significantly different from farmed animals in the body features, whereas the effect in highly productive animals is of special interest. We studied an influence of γ-irradiation on cAMP in Tsygai sheep for the first time and showed a cAMP modification both in the lymphocytes susceptible to radiation and in the thrombocytes which are relatively resistant.