2-METHYLPYRIDINIUM 5-(2,4-DINITROPHENYL)-6-OXO-2-THIOXO-1,2,3,6- TETRAHYDROPYRIMIDIN-4-OLATE: SYNTHESIS, CRYSTAL STRUCTURE, AND BIOLOGICAL EVALUATION

The titled complex is synthesized from the ethanolic solutions of 1-chloro-2,4-dinitrobenzene, 2-thiobarbituric acid, and 2-methylpyridine and characterized by spectral and elemental analyses. The single crystal X-ray diffraction results for the complex are compatible with the spectral observations. The titled complex exhibits anticonvulsant activity and reduces all phases of convulsion even at a low dosage. Acute toxicity studies of the complex are performed to understand the safer dose concentration for clinical trials.

• Kalaivani D.
• Mangaiyarkarasi G.
• Poornima DeviP.
• Sridevi G.

• Прикладные науки. Медицина. Технология

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